Generally, with respect to the holy Quran, ( according to Baqarah:115):
وَلِلَّـهِ الْمَشْرِقُ وَالْمَغْرِبُ ۚ فَأَيْنَمَا تُوَلُّوا فَثَمَّ وَجْهُ اللَّـهِ ۚ إِنَّ اللَّـهَ وَاسِعٌ عَلِيمٌ
And to Allah belongs the east and the west. So wherever you [might] turn, there is the Face of Allah. Indeed, Allah is all-Encompassing and Knowing.
But with respect to the holy Quran (and likewise narrations) according to other verse(s), we ought to do some deeds toward the Qiblah.
فَوَلِّ وَجْهَكَ شَطْرَ الْمَسْجِدِ الْحَرَامِ وَ حَيْثُ مَا كُنتُمْ فَوَلُّواْ وُجُوهَكُمْ شَطْرَهُ
We have certainly seen the turning of your face, [O Muhammad], toward the heaven, and We will surely turn you to a qiblah with which you will be pleased. So turn your face toward al-Masjid al-Haram. And wherever you [believers] are, turn your faces toward it [in prayer]. Indeed, those who have been given the Scripture well know that it is the truth from their Lord. And Allah is not unaware of what they do. (Surah Al-Baqarah: 114)
As a result, in accordance with the verse above, we ought to be toward Qiblah in our Salah.
On the other hand it has shown in the traditions that we must say prayers toward Qiblah.
حر عاملي، وسائل الشيعه، نشر دار الاحياء التراث العربي، بيروت 1412 ق. ج4، ص 295. (Hor Ameli, Wasael al Shia)
We can pay attention to the mentioned issue according to the issue of Unity. In truth, Muslims must pay attention that there must be a aim behind the issue. In fact, there must be a goal if Allah order us to prayer toward a specific place. Accordingly it could be rational that the significant point of the praying toward the Kabba is related to the unity of the Muslims. Since as you are aware, as a rule, have the unity will be the cause of the power between different Muslims of the world (in different country).
So, I assume you inquired a very significant issue, since it could remind us not to forget the significance of the unity (Wahdah) between Muslims.